Tuesday, March 25, 2025

Fiat and lux

Fra Angelico's Annunciation in Florence;
Mary heavy with the weight of her fiat
Fiat. It brought a universe into being. Fiat lux — let there be light. With a breath an unbearable radiance poured into the darkness. Fiat, said Mary to Gabriel. And with a breath that infinite, unbearable Light poured into a young woman in a small town, until she swayed with the weight of it. Fiat, cried Jesus in the garden of Gesthemane. Once again the universe was borne on a breath, carried across the shoulders of God incaranate.

We hear these assents as “let it be done to me.” Yet the Greek word Luke uses in this Gospel -- genoito -- means more than passive assent. It whispers of birth and growth, of what might we become. None of the events set in motion by these fiats are complete, they were each a “yes” to becoming. The light that tore through the darkness all those billions of years ago is still flaring out, igniting suns whose light will not reach us for a hundred billion years. 

Mary said yes to becoming the Christ-bearer. Even now she bears our prayers aloft, swaying under the weight of our needs.  And with a word ripped from the depths, Jesus became the redeemer of our sins past and present and even of the future. Light still careening through our darkness, moving heaven and earth. 

Light has no weight the physicists tell us. Except when it is in motion. Then it has power that can sweep the dust of dead stars together with enough force to bring the very earth we stand on into being. Dare I take on the weight of light? Dare I say “yes”  to moving toward what God hopes for me?  

FiatFiat lux. Let me be aflame with the Gospel, heavy with the light of Christ.

_____________

A version of this reflection appeared in Give Us This Day on March 25, 2023.


Thursday, March 13, 2025

Socks and the Second Law

 

The second law of thermodynamics can be framed as the desire for the universe for disorder. Things, left to their own devices, will get messier. Sorted stacks of papers gradually get scrambled. Ice melts. Socks become unpaired.

There were a weeks’s worth of socks, 8 pairs, in the laundry. What did I get back? Ten socks total - only 2 pairs. Where did the rest go? Great question. Entropy rules.


This present moment

In some sense it always Advent, even now in Lent. We are pilgrims, ever leaning into the future. To quote Walter Burghardt, SJ, “every tomorrow has it’s own tomorrow”. We are always waiting. Yet. Yet we are living now, in this precise moment. It is all we have. The past has slipped through our fingers, the future is for the moment unknowable. It can feel like we are merely marking time, or enduring the storms that rage. Yet. Yet we can live, not wrapped in our own thoughts, but awake to the needs that present themselves now, awake to each other, awake to God…

Walter Burghardt, SJ in an Advent homily.

“I have one swift answer: live in hope! Both words are important, indispensable, irreplaceable: hope and live. You must be men and women of ceaseless hope, because only tomorrow can today's human and Christian promised be realized; and every tomorrow will have its own tomorrow, world without end. Every human act, every Christian act, is an act of hope. But that means you must be men and women of the present, you must live this moment – really live it, not just endure it – because this very moment, for all its imperfection and frustration, because of its imperfection and frustration, is pregnant with all sorts of possibilities, is pregnant with the future, is pregnant with love, is pregnant with Christ.

If you want to lift Advent from liturgy to life, don't waste your days with sheer waiting. Wait indeed, for tomorrow promises to be rich in life and love. But life and love are here today, because God is here today — because your brothers and sisters are here today.”

 

Friday, March 07, 2025

Shout

 

Shout
Shout
Let it all out
These are the things I can do without
Come on
I'm talking to you
Come on

In violent times
You shouldn't have to sell your soul...

Forty years ago Tears for Fears released "Shout". I hadn't thought of the track in years but today as scientists and others gather to rally for science in the face of the cuts proposed by the current administration's unelected minions I find it running through my mind. Can we shout, make ourselves heard above the maelstrom that we are living through?

I am committed in the current moment to being noisy where I can. Like a great wind blowing, the current events are snatching our voices, drowning out the cries of the poor, the marginalized, the hungry, the sick, and the suffering with their drum beat of lies. The beating drums are meant to frighten, to shock into silence, to bewilder.

I wrote the op-ed that follows, which appeared in the Philadelphia Inquirer last month. I woke up at 3:45 in the morning with the question running through my head, "Is this what you voted for?" 

Know a Trump voter? Ask them, be specific. Did you vote for an increase in pediatric cancer deaths? Are you willing to forgo treatment with anything developed using funding by the NIH? Really? Have you have had shingles? No? You got the shot? Great, NIH funded. 

Shout.

The op-ed:

“This is what the people voted for.”or so we hear from the White House with each slashed program. But is it? Did people really vote to tear apart the National Institutes of Health (NIH) and lay waste to the nation’s scientific infrastructure? Perhaps you did, wondering what we get for our $48 billion every year.

I know what I have gotten: my life back. The pioneering work that led to the drug that I take for a neurodegenerative disease was done at the NIH, by a foreign scientist here on a visa. Without that drug I struggle to write on the blackboard, walk down the hallway, or even brush my teeth. It's not a cure, but with it I can work full time — and pay the taxes that help support the NIH.

I also know what others have gotten. When a teen-aged friend died of acute lymphoblastic leukemia (ALL) in the 1970s, survival rates were about 25%. Now 90% of children with ALL survive thanks in part to research supported by the NIH. 

A study by Ekaterina Cleary, Matthew Jackson, and Edward Zhou published in JAMA in 2023 showed that nearly every drug approved by the FDA between 2010 and 2019 was touched by NIH funding. Shingrix to prevent the misery of shingles. Dulaglutide to control blood sugar in type 2 diabetics. Stelara for Crohn’s disease. Lifesaving drugs for cancer, including Keytruda and aflibercept. My own research into the mechanism by which the anti-cancer drug taxol works was funded in part by the NIH.

Private investment in pharmaceutical research cannot replace the NIH. The work done by academic scientists is not proprietary and can be shared widely, amplifying the effect of our government investment. Commercial companies have a responsibility to shareholders, they cannot take as much of a risk as NIH funded projects can. Not every research project on lizard saliva will lead to a block buster drug (as it did for Ozempic) but some will. We need both public investment and the private sector to continue to be world leaders in health care.

But you voted to get rid of”wokeness” not real science, you say? The US has a high maternal and infant mortality rate, appallingly so for black women. Cancelling the research related to race keeps us from understanding why these disparities exist and what to do about them. Women and babies will continue to die. 

If ending public investment in biomedical research in the US is what you hoped for when you voted in the 2025 presidential election, then I expect you to look me in the eye and tell me you voted for me to be disabled and unemployed. I hope you can explain to your neighbor why her grandchild was stillborn and her daughter dead. Or tell your father that no cure for your mother’s Alzheimer’s disease is coming anytime soon. Because that’s what you voted for.

If this isn’t what you voted for, then I urge you to call your congressperson and your senator and tell them so. Before it's your life on the line.

___________
Photo is of molecular model of L-3,4-dihydroxyphenylalanine, L-DOPA, the standard of care for Parkinson's.



Monday, March 03, 2025

Aging with intensity

 

I love cut flowers, they feel like such a luxury. Right now there are sunflowers on the dining room table, and another vase of them on the passthrough by the kitchen sink. Roses from Math Man have just made their way to the compost, circling back to...tomatoes or basil.

Much as I love fresh flowers, I am fascinated with watching them age. These lilies were in my study at home, fading and drying, in their own way as beautiful as they were fresh cut. The colors intensify as the petals dry. Curves and ridges appear, reflecting the late afternoon light. And at the last there is a barely audible rustle as the petals surrender to gravity, one following another. When I go down for the day, I gather the fallen petals and pull the last few stems from the vase. Dust to dust.

Like the flowers, I am aging, though not that fast. Wondering if my colors will deepen, and whether my wrinkles will be as interesting in the late day sun. Will I rustle as I surrender bit by bit? (I feel more inclined to shout these days, but that's another post.)

I want to age intensely, intentionally. To offer up, rather than give in.